《植物生理学报》 2018, 54(4): 549-556

植物雷帕霉素靶蛋白(TOR)信号通路研究进展

赵珺玥¹, 范海延^1,2,*, 崔娜¹, 于洋¹, 王翔宇³, 杨芸¹

¹沈阳农业大学生物科学技术学院, 沈阳110866; ²沈阳农业大学设施园艺省部共建教育部重点实验室, 沈阳110866; ³沈阳农业大学园艺学院, 沈阳110866

通信作者：范海延；E-mail: hyfan174@163.com

摘　要：

雷帕霉素靶蛋白(TOR)是一种存在于真核生物中进化保守的丝氨酸/苏氨酸激酶, 通过调节细胞周期、蛋白质合成、细胞能量代谢等多种途径发挥重要的生理功能。作为真核生物生长发育与免疫应答中最重要且高度保守的宏观调控者之一, TOR已成为近年生物学领域一个新的研究热点。本文主要阐述了TOR在生物中高度保守和对雷帕霉素敏感的特性, 及其在拟南芥(Arabidopsis thaliana)、玉米(Zea mays)、豌豆(Pisum sativum)等植物中对生长、SnRK-TOR信号通路、糖代谢及防御反应的影响。

关键词：雷帕霉素靶蛋白; TOR信号; 植物生长; 植物代谢; 免疫应答

收稿：2018-01-10   修定：2018-03-20

资助：国家自然科学基金(31772314)、辽宁省自然科学基金重点项目(20170540802)和沈阳市科技计划项目(17-231-1-35)。

Research progress in plant target of rapamycin (TOR) signaling pathway

ZHAO Jun-Yue¹, FAN Hai-Yan^1,2,*, CUI Na¹, YU Yang¹, WANG Xiang-Yu³, YANG Yun¹

¹College of Biological Science and Technology, Shenyang Agricultural University, Shenyang 110866, China; ²Ministry of Education–Liaoning Province Key Laboratory of Facilities Horticulture, Shenyang Agricultural University, Shenyang 110866, China; ³College of Horticulture, Shenyang Agricultural University, Shenyang 110866, China

Corresponding author: FAN Hai-Yan; E-mail: hyfan174@163.com

Abstract:

Target of rapamycin (TOR) is a kind of evolutionarily conservative serine/threonine kinase existing in eukaryotes, and plays an important role in regulating cell cycle, protein synthesis, and cell energy metabolism. As one of the most important and highly conservative macro-regulators in the growth of eukaryote and immune response, TOR has become a new research hotspot in biology field in recent years. This paper mainly elaborates the high conservativity and sensitivity to rapamycin characteristics of TOR, and its impact on growth, sucrose nonfermentation–associated protein kinases (SnRKPT), TOR signaling pathway, glucose metabolism and defense response in plants such as Arabidopsis thaliana, Zea mays, Pisum sativum, etc.

Key words: target of rapamycin; TOR signaling; plant growth; plant metabolism; immune response